Lionel Messi will go into his second major international final in as many years hoping to finally lead Argentina to glory.
The Barcelona man has won everything there is to win in the club game, but is now looking to ease the pain from last summer's World Cup final defeat by lifting the Copa America.
But attempting to stop him and his team are host Chile, who have never won the competition and will be confident that they can end the drought in front of their own fans.
Join JONNY SINGER for all the action, with updates from MARTIN DOMIN in Santiago.
A word for the losers..
They weren't very good today, but you have to feel for Argentina - that's a World Cup and now the Copa America both lost in a final, within a year.
Three men in particular stand out for me.
Javier Mascherano, who gives everything, raises the level of his team-mates, and is the reason that a theoretically shaky defence rarely looks threatened. He deserves an international medal or two.
Gonzalo Higuain may only have himself to blame, but he will forever now be remembered as the man who cost his country. Twice. The miss in last year's final, the chance in stoppage time here (which was really Lavezzi's fault, but don't expect anyone to remember that) and then the penalty, blasted over the bar.
Last, but most definitely not least, Lionel Messi. The best player of his generation. Possibly the best of all time. In a system that doesn't really work he has helped his team to two major finals in two years. And both times, he has been let down by his team-mates. Yes, he wasn't at his best tonight, but he still created the chance that should have won it. Others have failed him.
What about that?
It's taken 99 years. 173 Copa America games. But Chile have finally won a major trophy.
They have probably been the best side at this tournament, scoring the most goals in the group stage, playing a pretty good brand of football, and, most importantly, holding their nerve when it mattered.
That Alexis Sanchez penalty, by the way, was the most ridiculously cool way to finish it off.
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